Diffuse Axonal Injury After Traumatic Brain Injury

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چکیده

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Progress of Research on Diffuse Axonal Injury after Traumatic Brain Injury

The current work reviews the concept, pathological mechanism, and process of diagnosing of DAI. The pathological mechanism underlying DAI is complicated, including axonal breakage caused by axonal retraction balls, discontinued protein transport along the axonal axis, calcium influx, and calpain-mediated hydrolysis of structural protein, degradation of axonal cytoskeleton network, the changes o...

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mental trauma experienced by caregivers of patients with diffuse axonal injury or severe traumatic brain injury

conclusions a long-term longitudinal study encompassing integrated research is needed to fully understand the traumatic experiences of caregivers. unless research on tbi or dai trauma is given its proper attention, the burden of trauma and injury on societies will continue to exacerbate globally. context as with care giving and rehabilitation in chronic illnesses, the concern with traumatic bra...

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Traumatic Brain Injury at Multiple Length Scales: Relating Diffuse Axonal Injury to Discrete Axonal Impairment

The length scales involved in the development of diffuse axonal injury, typically range from the head level (i.e., mechanical loading) to the cellular level, where discrete axonal injuries are located near inclusions. The aim is to investigate the local axonal strains near an inclusion in relation to the tissue level strains of the brain stem during mechanical loading of the head and the result...

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Abnormal corticospinal excitability in traumatic diffuse axonal brain injury.

This study aimed to investigate the cortical motor excitability characteristics in diffuse axonal injury (DAI) due to severe traumatic brain injury (TBI). A variety of excitatory and inhibitory transcranial magnetic stimulation (TMS) paradigms were applied to primary motor cortices of 17 patients and 11 healthy controls. The parameters of testing included resting motor threshold (MT), motor evo...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 2004

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-18-7-4